Year 4, 2012-13
Module leaders
Dr Ian F Godsland
Dr Kevin G Murphy
Endocrinology
Monday 12 November - Friday 14 December 2012

Module 2: Type 2 diabetes mellitus, metabolism and obesity - timetable [Word] updated 6/11/12

In-course assessment instructions [Word] Essay allocation [Excel] Journal clubs [Excel]

Diabetes tutorial groups [Excel] Diabetes tutorial 1: Diabetes in practice [Word]

Diabetes tutorial 2: Insulin resistance and secretion [Word]
Obesity and appetite tutorial groups [Excel] Tutorial 1: Techniques revision [Word]
Tutorial 2: Congenital obesity [Word]
Tutorial 3: Human studies [Word]
Tutorial 5: Anti-obesity drugs [Word]

PowerPoint presentations [learning objectives are Word files]:
Mon 12 Nov Introduction to obesity - Dr Kevin Murphy
Introduction to Type 2 DM - Dr Ian Godsland
History of diabetes - Dr Ian Godsland
Type 2 diabetes: the basics + learning objectives - Dr Ian Godsland
Tues 13 Nov Insulin resistance in the pathogenesis of T2DM + learning objectives - Dr Ian Godsland
Insulin secretion in the pathogenesis of T2DM + learning objectives - Dr Ian Godsland
Wed 14 Nov Pancreatic development and diabetes - Dr Gabriella da Silva Xavier

Molecular basis of insulin sensitivity - Dr Isabelle Leclerc
Thurs 15 Nov

The thrifty phenotype: Barker Hales hypothesis - Dr Stephen Robinson
Insulin resistance in pregnancy - Dr Stephen Robinson
Metabolism in obesity and T2DM + learning objectives - Dr Ian Godsland
Fri 16 Nov Hypothalamic appetite control + learning objectives - Dr Kevin Murphy
Leptin and insulin neuropeptide signalling + learning objectives - Dr Kevin Murphy

Hypothalamic nutrient and fuel sensing - Dr Gavin Bewick
Diabetes and cancer - Dr Daniel Morganstein
Tues 20 Nov Role of inflammation in T2DM + learning objectives - Dr Shivani Misra
Clinical assessment of insulin resistance - Dr Ian Godsland
Clinical assessment of insulin secretion + learning objectives - Dr Ian Godsland
Thurs 22 Nov T2DM prevention: what the trials tell us about pathogenesis - Dr Nick Oliver
Polycystic ovary syndrome and insulin resistance [pdf] - Dr Davinia White
Fatty acids and regulation of intermediary metabolism + learning objectives - Dr Ian Godsland
Fri 23 Nov Central regulation of energy expenditure - Dr Caroline Small
Ghrelin, PYY, PP and appetite - Dr Ben Field
Genetics of obesity - Dr Gavin Bewick
Adiponectin and the adipocytokines + learning objectives - Dr Kevin Murphy
Mon 26 Nov Insulin action and ovarian function [pdf] - Professor Stephen Franks
Tues 27 Nov Nuclear hormones and metabolism - Professor Malcolm Parker
The melanocortin system - Professor Waljit Dhillo

Hydroxysteroid dehydrogenase, cortisol and obesity - Dr Chris John
Wed 28 Nov

GLP-1: the future target for diabetes? - Dr Mark Edwards

Pre-proglucagon derived gut hormones and appetite - Dr Mark Edwards
Thurs 29 Nov The thrifty genotype - Dr Stephen Robinson

Debate: The primary defect in T2DM is insulin resistance - Dr Stephen Robinson
Debate: Insulin resistance is the cause - Dr Ian Godsland
The metabolic syndrome + learning objectives - Dr Ian Godsland
Fri 30 Nov Bariatric surgery - Dr Alexander Miras
Mon 3 Dec Brain stem and appetite regulation - Professor Waljit Dhillo
Opioids, cannabinoids and classical neurotransmitters - Professor Waljit Dhillo
Foetal programming - Dr Gavin Bewick
Tues 11 Dec

Anti-obesity drugs + learning objectives - Dr Kevin Murphy
Obesity: genes vs willpower - Dr Kevin Murphy, Dr Gavin Bewick

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