Year 4, 2012-13
Module leaders
Dr Anna Randi
Professor Alun Hughes
Dr Mike Schachter
Cardiovascular Sciences
Monday 12 November - Friday 14 December 2012

Module 2: Vascular biology and cardiovascular pharmacology - timetable for weeks 1-2 [Word]
- timetable for weeks 3-5 [Word]

PowerPoint presentations, unless otherwise indicated:
Mon 12 Nov

Introduction to the inflammatory pathobiology of atherosclerosis - Professor Dorian Haskard
Macrophages in atherosclerosis - Dr Joseph Boyle
Endothelium - Dr Michael Johns
Tues 13 Nov Leukocyte adhesion [pdf] - Dr Kevin Woollard
Flow, shear stress, the endothelium and atherosclerosis - Professor Justin Mason
Smooth muscle cells and atherosclerosis - Dr Paul Kemp
Endothelial mechanosensitive signalling pathways - Professor Rob Krams
Wed 14 Nov Von Willebrand Factor - Professor Mike Laffan
The multiple roles of thrombin in directing coagulation - Professor David Lane
Thurs 15 Nov Angiogenesis - Dr Graeme Birdsey
Angiogenesis and disease - Dr Anna Randi
Angiogenesis assays - Dr Richard Starke
Inflammatory pathways and the vasculature [pdf] - Professor Jane Mitchell
Regulation of vascular function by Rho GTPases - Dr Beata Wojciak-Stothard
Fri 16 Nov Ubiquitin and NF-κB activation [pdf] - Dr Maurice Darding
Serum and imaging biomarkers in atherosclerosis [pdf] - Dr Ramzi Khamis

Understanding atherosclerosis: the effects of shear stress in vitro [pdf] - Dr Damien Calay
Mon 19 Nov NFκB: The hub of innate immunity within the vascular vessel wall [pdf] - Dr Claudia Monaco

Clinical studies on inflammation during cardiopulmonary bypass - Dr Francesco Fiorentino
Side effects of CPB [pdf] - Professor Gianni Angelini
Mon 26 Nov Structure, function and diversity of the vasculature - Professor Steven Marston
Structure and function of vascular smooth muscle - Professor Steven Marston
Vascular tone and NO - Dr Adrian Chester
Tues 27 Nov Cardiorespiratory control mechanisms part 1 and part 2 [pdf] - Dr Charlotte Manisty
Excitation extraction coupling - Professor Alun Hughes
Wed 28 Nov Endothelial transport - Dr Darryl Overby
Renin-angiotensin system - Professor Alun Hughes
Thurs 29 Nov Pharmacogenetics - Dr Vincenzo Libri
Fri 30 Nov

Diabetes, macrovascular and microvascular disease - Professor Nish Chaturvedi
Introduction to pulmonary arterial hypertension - Dr Konstantinos Dimopoulos
Mon 3 Dec Drugs for ischaemic heart disease - Professor Jamil Mayet
Tues 4 Dec

Natriuretic peptides: physiology and therapeutic potential - Dr C Park
Wed 5 Dec Antiplatelet drugs - Dr Mike Schachter
Anticoagulant drugs - Dr Mike Schachter
Thurs 6 Dec Cardiovascular benefits of lipid-lowering drugs - Dr Mike Schachter
Aldosterone and endothelin antagonists - Dr Mike Schachter

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