Year 4, 2012-13
Module leaders
Dr Graham Taylor
Dr Samantha Sampson
Immunity and infection
Monday 12 November - Friday 14 December 2012

Module 2: Infection and host responses - timetable [Excel] updated 20/11/12

PowerPoint presentations, unless otherwise indicated:
Mon 12 Nov Introduction - Dr Samantha Sampson

Molecular basis of aspergillus host-pathogen interactions - Dr Elaine Bignell
Cryptococcus: host-pathogen interactions - Dr Elaine Bignell
Tues 13 Nov Concepts of virulence: animal models of funal infection - Dr Elaine Bignell
Aspergillus lung disease - Dr Rosemary Boyton
Thurs 15 Nov Candida: mucosal and systemic infections - Dr Darius Armstrong-James
Staphylococcus aureus - Dr Angelika Grundling
Fri 16 Nov Bacterial structures [pdf] - Dr Vladimir Pelicic
Biology of neisseria meningitidis [pdf] - Dr Vladimir Pelicic
Assignments and journal club - Dr Samantha Sampson
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria [pdf]
Mon 19 Nov Biology of an intracellular pathogen: salmonella - Dr Sophie Helaine
Bacterial autophagy [pdf] - Dr Teresa Thurston
Biology of pathogenic Escherichia coli [pdf] - Dr Nathalie Rolhion
Tues 20 Nov Primary immune deficiencies - Dr Peter Kelleher
Mtb 1: Physiology and life cycle - Dr Brian Robertson

Mtb 2: Host-pathogen interactions: innate immunity - Dr Brian Robertson
Thurs 22 Nov Mtb 3: Host-pathogen interactions: adaptive Immunity - Dr Brian Robertson
TB chemotherapy: past, present and future - Dr Kerstin Williams
Reading: Targeting persisters for tuberculosis control [pdf]
Global tuberculosis drug development pipeline: the need and the reality [pdf] The Lancet
Mechanisms of drug resistance in mycobacterium tuberculosis [pdf] - chapter 8 from Tuberculosis and the Tubercle Bacillus edited by Stewart T Cole et al, 2005 ASM Press, Washington DC
Data interpretation tutorial - Dr Samantha Sampson
Data interpretation exercise [Word] - Dr Samantha Sampson
Journal of Immunology article [pdf]

TB/HIV - Dr Graham Cooke
Fri 23 Nov TB vaccines [pdf] - Dr Samantha Sampson
Journal club [pdf] - Dr Samantha Sampson
Mon 26 Nov Introduction to retroviruses - Professor Myra McClure
Humoral immune response to HIV infection - Dr Simon Jeffs
Tues 27 Nov Cellular immune responses to HIV - Dr Sarah Fidler
Retroviral DNA integration [pdf] - Dr Goedele Maertens
HIV envelope - cellular interactions - Dr Simon Jeffs
Thurs 29 Nov HTLV-1 clinical presentations and virological outcomes [pdf] - Dr Graham Taylor
T cell dynamics and retroviral infection [pdf] - Professor Charles Bangham
Primary HIV infection - Dr Sarah Fidler
Mother-to-child HIV transmission [pdf] - Dr Graham Taylor
Fri 30 Nov Human Immunodeficiency Virus: HIV-1 - Professor Robin Shattock
Mon 3 Dec Antiretroviral therapy and immunomodulation - Dr Alan Winston
Leishmaniases and immunodeficiency [pdf] - Dr Ingrid Müller
Microbicides against HIV and STIs [pdf] - Dr Carolina Herrera
Tues 4 Dec Nosocomial infections - with focus on Gram-negative bacteria - Dr Elisabeth Kugelberg
HIV and the brain - Dr Alan Winston

Bacteriophage: from bacteria to efficient targeted systemic gene therapy - Dr Amin Hajitou

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