Year 4, 2012-13
Module leaders
Dr Ian Godsland
Dr Amir Sam
Endocrinology
Monday 8 October - Friday 9 November 2012

Module 1: Hormone-dependent systems and cancers - timetable [Excel] updated 22/10/12

Tutorial groups [Excel]

PowerPoint presentations [learning objectives are Word files]:
  In-course assessment exercise 1: Data interpretation [Word]
In-course assessment exercise 2: Essay [Word]
Mon 8 Oct Hormones and cancer: the basics + learning objectives - Dr Ian Godsland
Cancer and hormones: cancer therapy basics + learning objectives - Dr Ian Godsland
Tues 9 Oct Growth factors and tumour susceptibility genes + learning objectives - Dr Ian Godsland
Insulin and IGF-1 + learning objectives - Dr Ian Godsland
Apoptosis + learning objectives - Dr Ian Godsland
Diabetes and cancer - Dr Stephen Robinson
Thurs 11 Oct Cell adhesion, tissue integrity and angiogenesis in cancer - Dr Mark Sullivan
Tyrosine kinases as drug targets in cancer - Dr Nick Dibb
Mon 15 Oct The nuclear receptor superfamily + learning objectives - Dr Ian Godsland
Steroid receptors and their antagonists + learning objectives - Dr Ian Godsland
The science behind HRT - Dr John Stevenson
Tues 16 Oct Oestrogen receptors [pdf] - Professor Simak Ali
Endometrial carcinoma - Dr Sadaf Ghaem-Maghami
Progesterone receptors - Dr Jaya Nautiyal
Thurs 18 Oct Adrenal disease - Mr Fausto Palazzo
Pathology of breast cancer - Dr Mihr Gudi, Dr Thomas Lynch
Prostate cancer - Dr Charlotte Bevan
Progesterone signaling in breast and endometrial cancer - Dr Laki Buluwela
Control of steroid hormone production - Professor Stephen Franks
Mon 22 Oct Gut hormone tumours - Professor Waljit Dhillo
Principles of radioimmunoassay I - Professor Waljit Dhillo
Gut hormone tumours 2 - Professor Karim Meeran
Radioimmunoassay and its application in the diagnosis of endocrine disorders [Word]
Reading: Pancreatic cholera syndrome in a 42-year-old woman [pdf]
Everolimus for advanced pancreatic neuroendocrine tumors
Sunitinib malate for the treatment of pancreatic neuroendocrine tumors
Multiple endocrine neoplasias - Dr Duncan Bassett
Thurs 25 Oct Phaeochromocytomas and tumour markers - Dr Radha Ramachandran
Pituitary tumours: pathology - Dr Federico Roncaroli
Mon 29 Oct The TSH receptor as a paradigm for G-protein coupled receptors - Dr Duncan Bassett

Studies of G-protein-coupled receptors [pdf] - Scientific background on the Nobel Prize in Chemistry 2012
Tues 30 Oct General and clinical aspects of thyroid cancer - Mr Fausto Palazzo
Thurs 1 Nov Molecular biology of thyroid hormone secretion and action + learning objectives [pdf] - Professor Graham Williams
Mon 5 Nov Parathyroid disorders and the calcium sensing receptor - Dr Jeremy Cox

Pathophysiology of osteoporosis - Dr Jeremy Cox
Tues 6 Nov Bisphosphonates, statins and osteoporosis - Dr Mike Schachter
Molecular mechanisms of bone remodelling [pdf] - Dr Jeremy Cox
Thyroid function in pregnancy - Dr Stephen Robinson

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