Year 4, 2012-13 Module leaders
Professor Steven Marston
Cardiovascular Sciences Professor Ralph Knoell
Dr Cesare Terracciano
Monday 8 October - Friday 9 November 2012

Module 1: Molecular and cellular cardiology - timetable [Word] updated 16/10/12

PowerPoint presentations, unless otherwise indicated:
Mon 8 Oct Introduction - Professor Alun Hughes
Introduction - Dr Cesare Terracciano
Early heart development [pdf] - Professor Thomas Brand
Later stages of heart development [pdf] - Professor Thomas Brand
Tues 9 Oct Extracardiac cell populations [pdf] - Dr Jan Schlüter
The zebrafish as a model for studies of development and diseases [pdf] - Dr Kar Lai Poon
Congenital heart disease [pdf] - Professor Thomas Brand
Mechanism of cardiac muscle contractility - Dr Hind Al-Khayat
First steps in statistical analysis - Professor Alun Hughes
Wed 10 Oct Electrophysiological techniques - Dr Cesare Terracciano
The origin of the resting membrane potential - Dr Ken MacLeod
Measurement of membrane currents and mechanisms of channel gating - Dr Ken MacLeod
Thurs 11 Oct Principles of electrical wave propagation in the heart [pdf] - Dr Alexander Lyon
The cardiac action potential - Dr Ken MacLeod
Fri 12 Oct Ion transporters and ionic regulation in cardiac cells - Dr Ken MacLeod
Calcium regulation in the heart: ion transporters - Dr Cesare Terracciano
Calcium regulation in the heart: excitation contraction coupling - Dr Cesare Terracciano
Mon 15 Oct

Calcium regulation in the heart: excitation contraction coupling 2 - Dr Cesare Terracciano
Force frequency relationship and other contractile phenomena - Dr Ken MacLeod
A cellular basis for cardiac arrhythmias - Dr Ken MacLeod
Tues 16 Oct Derangements to ionic currents in cardiac hypertrophy and failure - Dr Cesare Terracciano
Wed 17 Oct Overview of heart diseases [pdf] - Professor Ralph Knöll
Adrenergic signalling in the heart - Professor Sian Harding
Thurs 18 Oct Journal club: Physiology [Word]
Fri 19 Oct Hypertrophic cardiomyopathy [pdf] - Professor Ralph Knöll
Arrhythmogenic right ventricular cardiomyopathy (ARVC) [pdf] - Professor Ralph Knöll
Cardiac fibroblasts [pdf] - Dr Patrizia Camelliti
Myocyte function in hypertrophy and heart failure - Professor Sian Harding
Mon 22 Oct Cardiac gene therapy [pdf] - Dr Alexander Lyon
Journal club: Myocardial genetics [Word]
Tues 23 Oct hESC and iPS cells - Professor Sian Harding
Alteration of extracellular matrix in the heart during remodelling - Dr Priyanthi Dias
Fri 26 Oct Cell therapy - Professor Sian Harding
Cardiac tissue engineering - Professor Sian Harding
Mon 29 Oct Journal club: Regeneration [Word]

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