Year 4, 2011-12
Module leader
Dr Robert Dickinson
Pharmacology
Monday 10 October - Friday 11 November 2011

Module 1: Principles of pharmacodynamics and pharmacokinetics - timetable [Word]

COURSEWORK SUBMISSION
Please submit your coursework for this module at the portal. Select the "BSc1112-PHARM-mod1-ICA" option
Deadline is 5pm, Monday 14th November, after which penalties for late submission my apply

PowerPoint presentations, unless otherwise indicated:
Mon 10 Oct Pharmacokinetics: single and multi-compartment models 1 [pdf] - Dr Robert Dickinson
Diffusion and active transport / Transport of drugs across biological membranes [pdf] - Dr Toby Athersuch
Tues 11 Oct Pharmacokinetics: single and multi-compartment models 2 [pdf] - Dr Robert Dickinson
Pharmacokinetics and drug bioavailability [pdf] - Dr Jake Bundy
P-Glycoprotein and the removal of drugs from cells [pdf] - Dr Toby Athersuch
Analysis of drug transport across cell membranes [pdf] - Dr Toby Athersuch

Principles of pharmacogenetics [pdf] - Dr Marc-Emmanuel Dumas
Thurs 13 Oct Phase 1 polymorphisms [pdf] - Dr Marc-Emmanuel Dumas
The blood brain barrier - Dr Elizabeth Want
Principles of PKPD: drug metabolism - Dr Muireann Coen
Tues 18 Oct The placenta, teratogenicity and fetal origin of disease - Dr Elizabeth Want
Enzymes as drug targets [pdf] - Dr Marc-Emmanuel Dumas
Nuclear receptors [pdf] - Dr Marc-Emmanuel Dumas
Principles of PKPD: drug metabolism 2 - Dr Muireann Coen
Wed 19 Oct Principles of PKPD: preclinical models in toxicity [pdf] - Dr Muireann Coen
Fri 21 Oct Pharmacogenomics and pharmacometabonomics [pdf] - Dr Marc-Emmanuel Dumas

Structural analysis of drugs and their targets [pdf] - Dr Toby Athersuch
Phase 2 polymorphisms [pdf] - Dr Marc-Emmanuel Dumas
Tues 25 Oct Pharmacodynamics and receptors [pdf] - Dr Robert Dickinson
Drug interactions, adverse drug reactions, idiosyncratic toxicity - Dr Muireann Coen
Thurs 27 Oct Molecular targets of general anaesthetics [pdf] + handout [Word] - Dr Robert Dickinson
Pharmacology in action: drug MOAs in hypertension + part 2 [pdf] - Dr Toby Athersuch
Fri 28 Oct

Neuropharmacology research workshop:
Understanding general anaesthesia using electrophysiology [pdf] - Dr Robert Dickinson
Potassium channels [pdf] - Dr Stefan Trapp
Mon 31 Oct Molecular modelling in drug development [pdf] - Dr Toby Athersuch
Biological substances as drugs including gene therapy - Dr Elizabeth Want
Mon 7 Nov

Evolutionary conservation of drug actions [pdf] - Dr Giorgio Gilestro
Pharmacological targets for ethanol in the brain - Dr Catriona Houston

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