Year 4, 2011-12
Module leaders
Dr Anna Randi
Professor Alun Hughes
Dr Mike Schachter
Cardiovascular Sciences
Monday 14 November - Friday 16 December 2011

Module 2: Vascular biology and cardiovascular pharmacology - timetable: weeks 3-5 [Word]

Journal club groups [Excel]

PowerPoint presentations, unless otherwise indicated:
Mon 14 Nov Introduction to atherosclerosis [pdf] - Professor Dorian Haskard
Flow, shear stress, the endothelium and atherosclerosis - Professor Justin Mason
Tues 15 Nov Leukocyte adhesion: mechanisms and applications [pdf] - Miss Ellie Hughes
T-cells and atherosclerosis - Professor Marlene Rose
Ubiquitin in NF-κB activation [pdf] - Professor Henning Walczak
Smooth muscle cells and atherosclerosis - Dr Paul Kemp
Wed 16 Nov Von Willebrand factor - Professor Mike Laffan
Thrombin: its multiple roles in directing haemostasis - Professor David Lane
Thurs 17 Nov Angiogenesis [pdf] - Dr Ewa Paleolog
Angiogenesis assays - Dr Graeme Birdsey
Inflammation pathways and the vasculature [pdf] - Professor Jane Mitchell
Regulation of vascular function by Rho GTPases - Dr Beata Wojciak-Stothard
Fri 18 Nov Macrophages and atherosclerosis - Dr Yu Liu
NFκB: the hub of innate immunity in atherosclerosis [pdf] - Dr Claudia Monaco
Mon 21 Nov Shear stress, inflammation and atherosclerosis - Professor Rob Krams
Atherosclerosis and fluid mechanics [pdf] - Professor Ross Ethier
Side effects of CPB: what is the reality? - Professor Gianni Angelini
Mon 28 Nov Structure, function and diversity of the vasculature [pdf] - Professor Steven Marston
Structure and function of vascular smooth muscle [pdf] - Professor Steven Marston
Vascular tone and NO - Dr Adrian Chester
Tues 29 Nov Lipid transport + figures + handout - Professor Peter Weinberg

Excitation contraction coupling - Professor Alun Hughes
Autonomic control of blood vessels - Professor Alun Hughes
Wed 30 Nov Renin angiotensin system - Professor Alun Hughes
Natriuretic peptides: physiology and therapeutic potential - Professor Alun Hughes
Thurs 1 Dec Pharmacogenetics [pdf] - Professor Martin Wilkins
Fri 2 Dec Pharmacology of heart failure - Professor Sian Harding
Introduction to pulmonary arterial hypertension [pdf] - Dr Konstantinos Dimopoulos
Mon 5 Dec Anti-obesity drugs [pdf] - Dr Vian Amber
Therapeutics of chronic heart failure [pdf] - Dr Darrel Francis
Tues 6 Dec Pharmacological basis of antihypertensive therapy - Dr Neil Chapman
Drugs for ischaemic heart disease - Professor Jamil Mayet
Wed 7 Dec Anticoagulant drugs - Dr Mike Schachter
Thurs 8 Dec Cardiovascular benefits of lipid-lowering drugs - Dr Mike Schachter
Cardiovascular disease and diabetes - Professor Desmond Johnston
Fri 9 Dec Aldosterone and endothelin antagonists - Dr Mike Schachter
Antiplatelet drugs - Dr Mike Schachter

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