Year 4, 2011-12
Module leaders
Dr Graham Taylor
Dr Samantha Sampson
Immunity and infection
Monday 14 November - Friday 16 December 2011

Module 2: Infection and host responses - timetable [Excel]

Please submit your in-course assessment by logging into Blackboard and selecting the course entitled Year 4: Immunity & Infection BSc. Submission deadline: 16 December at 4 pm.
PowerPoint presentations, unless otherwise indicated:
Mon 14 Nov Introduction - Dr Samantha Sampson, Dr Graham Taylor
Molecular basis of aspergillus host-pathogen interactions - Dr Elaine Bignell
Cryptococcus: host-pathogen interactions - Dr Elaine Bignell
Tues 15 Nov Candida: mucosal and systemic infections - Dr Ana Maria Calcagno
Allergic bronchopulmonary aspergillosis - Dr Rosemary Boyton
Concepts of virulence: animal models of fungal infection - Dr Elaine Bignell
Thurs 17 Nov Fungal immunity and immunotherapy [pdf] - Dr Darius Armstrong-James
Staphylococcus aureus - Dr Angelika Grundling
Fri 18 Nov Structure of bacterial pathogens [pdf] - Dr Vladimir Pelicic
Biology of neisseria meningitidis [pdf] - Dr Vladimir Pelicic
Mon 21 Nov Biology of salmonella [pdf] - Professor David Holden
Biology of pathogenic escherichia coli [pdf] - Dr Nathalie Rolhion
Mtb 1: physiology and life cycle - Dr Brian Robertson
Tues 22 Nov

Mtb 2: Host-pathogen interaction: innate immunity - Dr Brian Robertson

Mtb 3: Host-pathogen interactions: adaptive Immunity - Dr Brian Robertson

Tuberculosis chemotherapy: past, present and future - Dr Kerstin Williams
Tuberculosis sanatorium regimen in the 1940s: a patient's personal diary - Journal of the Royal Society of Medicine, vol 97, July 2004
Global tuberculosis drug development pipeline: the need and the reality [pdf] - The Lancet, 19 May 2010
Mechanisms of drug resistance in mycobacterium tuberculosis [pdf] - chapter 8 from Tuberculosis and the Tubercle Bacillus edited by Stewart T Cole et al, 2005 ASM Press, Washington DC
Wed 23 Nov Data interpretation exercise + handout [Word] - Dr Samantha Sampson

IFN-α/β Signaling Is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis - The Journal of Immunology
Thurs 24 Nov TB vaccines: old and new - Dr Samantha Sampson
M tuberculosis ESX virulence locus - Dr Samantha Sampson
TB diagnotiscs - Dr Suzie Hingley-Wilson
Fri 25 Nov Strain diversity in mycobacterium tuberculosis [pdf] - Dr Nitya Krishnan
TB and HIV co-infection [pdf] - Dr Graham Cooke
HIV and hepatitis co-infection [pdf] - Dr Graham Cooke
TB-IRIS [pdf] - Dr Graham Cooke
Mon 28 Nov Humoral immune response to HIV infection - Dr Simon Jeffs
HIV vaccines - Dr Simon Jeffs
Tues 29 Nov Retroviral DNA integration [pdf] - Dr Goedele Maertens
Cellular immune responses to HIV - Dr Sarah Fidler
Thurs 1 Dec HTLV-1: is viral load the key to everything? - Dr Graham Taylor
T cell dynamics and retroviral infection - Professor Charles Bangham
Primary HIV infection - Dr Sarah Fidler
Fri 2 Dec Preventing transmucosal infection - Professor Robin Shattock
How will we prevent HIV infection? - Professor Jonathan Weber
Mon 5 Dec Antiretroviral therapy and immunomodulation [pdf] - Dr Alan Winston
HIV and the brain [pdf] - Dr Alan Winston
Leishmaniases and immunodeficiency - Dr Ingrid Müller
Tues 6 Dec Primary immune deficiencies - Dr Peter Kelleher
Systemic gene therapy with bacteriophage vectors - Dr Amin Hajitou

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