Year 4, 2011-12
Module leaders
Dr Ian F Godsland
Dr Kevin G Murphy
Endocrinology
Monday 14 November - Friday 16 December 2011

Module 2: Type 2 diabetes mellitus, metabolism and obesity - timetable [Word]

Please submit your in-course assessment for module 2 by logging into Blackboard and selecting Year 4: Endocrinology BSc. The deadline is 2 December 2011 at 5 pm.
In-course assessment guidelines [Word] Essay allocations [Excel] Journal clubs [Excel]

Diabetes tutorial groups [Excel] Diabetes tutorial 1: Diabetes in practice [Word]

Diabetes tutorial 2: Insulin resistance and secretion [Word]
Obesity and appetite tutorial groups [Excel] Tutorial 1: Techniques revision [Word]
Tutorial 2: Congenital obesity [Word]
Tutorial 3: Human studies [Word]
Tutorial 5: Anti-obesity drugs [Word]

PowerPoint presentations [learning objectives are Word files]:
Mon 14 Nov Introduction - Dr Ian Godsland
A brief history of the hypothalamus and obesity - Dr Kevin G Murphy

History of type 2 diabetes - Dr Ian Godsland

Diabetes: the basics + learning objectives - Dr Ian Godsland
Tues 15 Nov Insulin resistance in the pathogenesis of type 2 diabetes mellitus - Dr Ian Godsland

Insulin secretion in the pathogenesis of type 2 diabetes mellitus + learning objectives - Dr Ian Godsland
Wed 16 Nov Pancreatic development and diabetes + learning objectives - Dr Gabriela da Silva Xavier
Molecular basis of insulin sensitivity - Dr Isabelle Leclerc
Thurs 17 Nov The thrifty phenotype: Barker-Hales hypothesis - Dr Stephen Robinson
Pregnancy, insulin resistance and foetal growth - Dr Stephen Robinson
Metabolism in obesity and T2DM + learning objectives - Dr Ian Godsland
Fri 18 Nov Hypothalamic appetite control + handout - Dr Kevin G Murphy
Leptin and insulin hypothalamic signalling + learning objectives - Dr Kevin G Murphy
Central regulation of energy expenditure (EE) - Dr Caroline Smal
Tues 22 Nov Clinical assessment of insulin resistance - Dr Ian Godsland

Clinical assessment of insulin secretion + learning objectives - Dr Ian Godsland
Thurs 24 Nov Type 2 diabetes prevention: what trials tell us about pathogenesis [pdf] - Dr Nick Oliver
Polycystic ovary syndrome and insulin resistance [pdf] - Dr Davinia White
Fatty acids and regulation of intermediary metabolism + learning objectives - Dr Ian Godsland

Metabolic basis for dyslipidaemia in type 2 diabetes [pdf] - Dr Jonathan Valabhji
Mon 28 Nov Insulin action and ovarian function [pdf] - Professor Stephen Franks
Nuclear hormones and metabolism - Professor Malcolm Parker
Hypothalamic nutrient and fuel sensing - Dr Gavin Bewick
Tues 29 Nov Ghrelin, PYY, PP and appetite [pdf] - Dr Ben Field
The melanocortin system - Professor Waljit Dhillo
Hydroxy-steroid dehydrogenase, cortisol and obesity + learning objectives - Professor Julia Buckingham
Wed 30 Nov GLP-1: the future target for diabetes? - Dr Mark Edwards
Pre-proglucagon derived gut hormones and appetite - Dr Mark Edwards
Thurs 1 Dec The thrifty genotype - Dr Stephen Robinson
Inflammation in the pathogenesis of type 2 diabetes mellitus + learning objectives - Dr Shivani Misra

The metabolic syndrome + learning objectives - Dr Ian Godsland
Fri 2 Dec Foetal programming - Dr Gavin Bewick
Mon 5 Dec Brain stem and appetite regulation - Professor Waljit Dhillo
Opioids, cannabinoids and classical neurotransmitters - Professor Waljit Dhillo
Diabetes and cancer - Dr Daniel Morganstein
Genetics of obesity - Dr Gavin Bewick
Adiponectin and the adipocytokines + learning objectives - Dr Kevin G Murphy
Mon 12 Dec Anti-obesity drugs + learning objectives - Dr Kevin G Murphy

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