Year 4, 2011-12
Module leaders
Dr Ian Godsland
Dr Alan Purohit
Endocrinology
Monday 10 October - Friday 11 November 2011

Module 1: Hormone-dependent systems and cancers - timetable [Word]

PowerPoint presentations [learning objectives are Word documents]:
Mon 10 Oct The nuclear receptor superfamily + learning objectives - Dr Ian Godsland
Steroid receptors and their antagonists + learning objectives - Dr Ian Godsland
Control of steroid hormone production [pdf] - Professor Stephen Franks
Tues 11 Oct How does gene regulation control gene expression? - Professor Malcolm Parker

Progesterone receptors + references [Word] - Dr Jaya Nautiyal
Wed 12 Oct Oestrogen receptors - Professor Simak Ali

Tissue availability of steroid hormones - Dr Alan Purohit
Thurs 13 Oct Cancer and hormones: the basics + learning objectives - Dr Ian Godsland
Growth factors and tumour susceptibility genes + learning objectives - Dr Ian Godsland
Fri 14 Oct Cancer and hormones: Insulin and IGF-1 + learning objectives - Dr Ian Godsland
Mon 17 Oct Radioimmunoassay and its application in the diagnosis of endocrine disorders [Word]
Principles of radioimmunoassay - Professor Waljit Dhillo
Gut hormone tumours - Professor Waljit Dhillo
Gut hormone tumours 2 - Professor Karim Meeran
Apoptosis + learning objectives - Dr Ian Godsland

Control and inhibition of tumour angiogenesis - Dr Alan Purohit
Tues 18 Oct Ovarian cancer - Peter Mason
Pathology of breast cancer - Dr Gemma Petts

Tissue integrity and angiogenesis in cancer - Dr Mark Sullivan
Thurs 20 Oct Epigenetics and cancer 1 [pdf] - Dr Constanze Zeller
Epigenetics and cancer 2 [pdf] - Dr Nadine Chapman-Rothe

Molecular profiling - Dr Euan Stronach
Fri 21 Oct Progesterone in breast and endometrial cancer - Dr Laki Buluwela

Prostate cancer - Dr Charlotte Bevan
Mon 24 Oct Aromatase and cancer and ArKO and ERKO - Dr Alan Purohit
Steroid sulphatase inhibitors - Dr Alan Purohit
Tues 25 Oct In vivo tumour models - Dr Alan Purohit
Tyrosine kinases as drug targets in cancer - Dr Nick Dubb
Cell surface receptor signalling [Word] - Dr Nick Dubb
Thurs 27 Oct Drug resistance and cancer - Dr Jo Day
Mon 31 Oct Castration resistant prostate cancer (CRPC) - Dr Alan Purohit
Tues 1 Nov Thyroid hormone action [pdf] + learning objectives - Professor Graham Williams
Molecular biology of thyroid hormone secretion and action learning objectives - Professor Graham Williams
Fri 4 Nov Multiple endocrine neoplasias and the success of positional cloning? [pdf] + handout version [pdf] + learning objectives - Dr Duncan Bassett

The TSH receptor as a paradigm for G-protein coupled receptors in endocrinology [pdf] + handout version [pdf] + learning objectives - Dr Duncan Bassett
Mon 7 Nov Thyroid physiology and thyroid disease in pregnancy - Dr Stephen Robinson
Tues 8 Nov Bisphosphonates and statins - Dr Mike Schachter
The science behind HRT [pdf] - Dr John Stevenson

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