Year 4, 2012-13
Module leaders
Dr Marco Purbhoo
Dr Ashley Brown
Gastroenterology and Hepatology
Wednesday 2 January - Friday 1 February 2013

Module 3: Infective, immunological and inflammatory mechanisms in gut and liver disease
- timetable [Word] updated 16/1/13

PowerPoint presentations, unless otherwise indicated:
Wed 2 Jan Introduction - Dr Marco Purbhoo
Thurs 3 Jan The adaptive immune response - Dr Marco Purbhoo
Fri 4 Jan The humoral immune response - Professor Marina Botto
Regulatory T cells and role in liver disease [pdf] - Dr Maria Serena Longhi
Mon 7 Jan Interferons and the innate immune response [pdf] - Dr Michael McGarvey
Tues 8 Jan Introduction to molecular biology - Dr Marco Purbhoo
Wed 9 Jan Mechanisms of immune mediated drug hepatotoxicity [pdf] - Professor Alan Boobis
Tolerance and organ-specific autoimmunity - Dr Ruth Tarzi
Thurs 10 Jan Induction of tolerance to self-antigens - Professor Julian Dyson
Fri 11 Jan Pathology of autoimmune hepatitis - Professor Robert Goldin
Viral structure and replication of HCV [pdf] - Dr Michael McGarvey
Mon 14 Jan Immune mediated mechanisms of ALD and AIH - Dr Harry Antoniades

Immune defence of the liver and GI tract - Dr Marco Purbhoo
Tues 15 Jan HBV and HDV [pdf] - Dr Michael McGarvey
Wed 16 Jan Mechanisms of immune rejection + learning objectives [Word] - Professor Andrew George
Viral structure and replication of HAV and HEV [pdf] - Dr Michael McGarvey
Thurs 17 Jan HIV and the gastrointestinal tract - Dr Peter Kelleher
Host genetic effect on HBV and HCV infection - Dr Susanne Knapp
Fri 18 Jan Immune responses in IBD - Professor Tim Orchard
Mon 21 Jan Epidemiology and natural history of infection with hepatitis A-E viruses - Dr Janice Main
Traveller’s diarrhoea - Dr Ashley Whittington
Schistosomiasis and the liver - Professor Alan Fenwick
Tues 22 Jan Acute graft versus host disease - Professor Anastasios Karadimitris
Immune mechanisms of coeliac disease - Dr Peter Kelleher
Wed 23 Jan Opportunistic infections in the liver - Dr Khaleel Jamil
Thurs 24 Jan Liver abscesses and other infections - Dr Janice Main
Treatment of hepatitis C - Dr Janice Main
Molecular diagnostics and their importance - Dr Wafa Khamri
Fri 25 Jan Pathology of Chronic Viral Hepatitis - Professor Robert Goldin
Mon 28 Jan Steatohepatitis: science of inflammatory damage - Dr Nikhil Vergis
New approaches to treatment of viral infections-HBV and HCV [pdf] - Dr Michael McGarvey
Tues 29 Jan

The immune response to hepatitis viruses and vaccines - Dr Marco Purbhoo
Wed 30 Jan Collectins and defensins in the gut - Dr Wafa Khamri
Assessment of T cell function - Dr Wafa Khamri

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