Year 4, 2011-12
Surgery and anaesthesia - news and views articles
 

Development of personalized tumor biomarkers using massively parallel sequencing
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial - The Lancet [pdf]
Therapeutic delivery of miR-26a inhibits cancer cell proliferation and induces tumor-specific apoptosis
Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion
DNA damage signaling in response to double-strand breaks during mitosis
Generation of induced pluripotent stem cells using recombinant proteins
Design and validation of a metabolic disorder resequencing microarray (BRUM1)
Inhibition of poly (ADP-Ribose) polymerase in tumors from BRCA mutation carriers
Progesterone induces adult mammary stem cell expansion
DNA vaccination with T-cell epitopes encoded within Ab molecules induces high-avidity anti-tumor CD81 T cells
CD133 expression is not restricted to stem cells, and both CD133+ and CD133–metastatic colon cancer cells initiate tumors
DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies
Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix
Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth
Identification of selective inhibitors of cancer stem cells by high-throughput screening
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
PTC124 targets genetic disorders caused by nonsense mutations
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Early oncologic outcomes of robotic vs open radical cystectomy for urothelial cancer
Oncolytic reovirus effectively targets breast cancer stem cells
siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer
Expression of focal adhesion kinase in small-cell lung carcinoma
Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk - The Lancet [pdf]
Association of body mass index in early adulthood and middle age with future site-specific cancer mortality: the Harvard Alumni Health Study
The effects of Metformin on the survival of colorectal cancer patients with diabetes mellitus

Olaparib in patients with recurrent high-grade serous or poorly diff erentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study - The Lancet [pdf]
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms...
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
Treatment of advanced hepatocellular carcinoma with very low levels of amplitude-modulated electromagnetic fields
The telomerase activator TA-65 elongates short telomeres and increases health span of adult⁄old mice without increasing cancer incidence
Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases
Intraoperative tumor-specific fluorescence imaging in ovarian cancer...
Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction
Mesenchymal stem cells induce resistance to chemotherapy through the Release of platinum-induced fatty acids
Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma

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